姓名：郑道琼
职称：教授
学术职衔：博士生导师
研究方向：海洋微生物学，基因组学和遗传进化育种
电子邮箱：zhengdaoqiong@zju.edu.cn
学习工作简历
2021.01至今，浙江大学，教授
2014.04–2020.12，浙江大学，讲师、副教授
2014.09–2016.12，美国杜克大学访问学者/博士后
2007.09–2012.06，浙江大学生命科学学院，博士生
教学情况
讲授《海洋微生物学及实验》、《生物信息学》。
科研项目
[1] 特色酵母模型中探究eccDNA的形成机制及遗传稳定性，国家自然科学基金，32170078， 2022/01-2025/12.
[2] 国家重点研发计划子课题——酵母底盘合成医用多糖，2021YFC2103200， 2021/12-2024/11.
[3] 国家重点研发计划子课题——污染物降解酵母底盘的构建和适应进化，2020YFA0909500， 2021/12-2025/11.
[4] 酵母遗传学和基因组学，国家自然科学基金优秀青年基金，32022004，150万，2021/01-2023/12.
近5年代表性论文著作
[1]Lei Qi, Yang Sui, Xing-Xing Tang, Ryan J McGinty, Xiao-Zhuan Liang, Margaret Dominska, Ke Zhang, Sergei M Mirkin,Dao-Qiong Zheng*, Thomas D Petes*.Shuffling the yeast genome using CRISPR/Cas9-generated DSBs that target the transposable Ty1 elements.PLoS Genetics, 19(1):e1010590, 2023.
[2]Zhang K, Sui Y, Li W, Chen G, Wu XC, Kokoska R, Petes TD*,Dao-Qiong Zheng*.Global genomic instability caused by reduced expression of DNA polymerase ε in yeas. Proc Natl Acad Sci U S A, 119(12): e2119588119,2022.
[3]Zheng D Q, Wang Y T, Zhu Y X, et al. Uncovering bleomycin-induced genomic alterations and underlying mechanisms in yeast. Applied and Environmental Microbiology, 88(2):e0170321, 2022.
[4]Yang Sui, Lei Qi, Jian-Kun Wu, Xue-Ping Wen, Xing-Xing Tang, Zhong-Jun Ma, Xue-Chang Wu, Ke Zhang*, Robert J. Kokoska,Dao-Qiong Zheng*, Thomas D. Petes*. Genome-wide mapping of spontaneous genetic alterations in diploid yeast cells.Proc Natl Acad Sci U S A, 117(45):28191-28200, 2020.
[5]Yang Sui, Lei Qi, Ke Zhang, Natalie Saini, Leszek J. Klimczak, Cynthia J. Sakofsky, Dmitry A. Gordenin, Thomas D. Petes*,Dao-Qiong Zheng*. Analysis of APOBEC-induced mutations in yeast strains with low levels of replicative DNA polymerases.Proc Natl Acad Sci U S A, 117(17), 2020.
[6]Ke Zhang1,Dao-Qiong Zheng1,*, Yang Sui, Lei Qi, Thomas D. Petes*. Genome-wide analysis of genomic alterations induced by oxidative DNA damage in yeast. Nucleic Acids Research, 47(7), 2019.
[7]Lei Qi1, Ke Zhang1, Yu-Ting Wang, Jian-Kun Wu, Yang Sui, Xiao-Zhuan Liang, Lin-Zi Yu, Xue-Chang Wu, Pin-Mei Wang, Jin-Zhong Xu andDao-Qiong Zheng*.Global analysis of furfural-induced genomic instability using a yeast model. Applied and Environmental Microbiology. 85(18), 2019.
[8]Huan Sheng1, Lei Qi1, Yang Sui, Yu-Zhe Li, Ke Zhang, Jin-Zhong Xu, Pin-Mei Wang*,Dao-Qiong Zheng*. Mapping chromosomal instability induced by small-molecular therapeutics in a yeast model. Applied Microbiology and Biotechnology. 103(12), 4869-4880, 2019.
指导学生竞赛、创新训练
指导国家级、省级大学生创新创业训练计划多项
获得学术奖励
1.2020，国家自然科学基金优青项目。
社会兼职
浙江省微生物学会理事，浙江省药学会海洋药物青年委员会副主任，BMC Genomics、Marine Biotechnology等杂志编委
