郭宝英，教授，博士，博士生导师，科学技术处副处长，妇联副主席（兼），浙江省海洋增养殖工程技术研究中心副主任，美国Auburn University和University of Georgia访问学者。舟山市第七届青年科技奖获得者，舟山市“三八”红旗手。主要从事海洋生物分子遗传与进化、分子免疫与环境毒理等教学与研究工作，先后主持国家自然科学基金面上项目、国家自然科学基金重点国际合作项目子课题、科技部港澳台科技合作专项项目、国家自然科学基金青年项目、农业部渔业渔政局物种资源保护项目、浙江省自然科学基金重点项目、面上项目、浙江省科技厅项目、浙江省“三农九方”科技协作计划“揭榜挂帅”项目、舟山市科技局海洋专项项目等多项科研项目，参与科技部重点计划“蓝色粮仓”项目、省部级及以上项目多项。发表SCI期刊论文70余篇。
研究方向：
海洋生物分子遗传与进化
海洋生物养殖生境重塑与保护
分子免疫与环境毒理
校内外学术及行政兼职：
浙江省科协第十一届委员会委员，中国水产学会水产动物免疫学专业委员会委员、中国生物信息学学会（筹）农林信息学专业委员会委员，浙江省生物信息学会海洋生物分会副主任委员，舟山市欧美同学会理事、舟山市女科技工作者协会副理事。担任中国科协科技期刊卓越行动计划项目会评专家、中国科协财政项目评审专家、国家自然科学基金项目通讯评议专家、教育部研究生学位论文通讯评议专家、浙粤鄂鲁沪科技项目评审专家、舟山市重大决策社会风险评估专家等。Frontiers in Marine Science客座编辑、Science of the Total Environment、Scientific Reports、Conservation Genetics、Gene、水生生物学报、中国海洋大学学报等期刊审稿人。
学习工作经历：
2009.07---至今浙江海洋大学，讲师、副教授、教授
2018.12---2020.02国家自然科学基金委，挂职
2015.09---2016.09 University of Georgia，访问学者
2013.11---2014.11 Auburn University和University of Georgia，访问学者
2004.09---2009.06 华中农业大学水产学院，博士
2000.09---2004.07 鲁东大学生命科学学院，学士
科研项目：
1.国家自然科学基金重点国际合作项目：海洋贻贝环境适应的免疫独特性的发现与挖掘，42020104009，265万元，2021.01-2025.12，子课题负责人
2.国家自然科学基金面上项目：基于全基因组测序探索中国沿海两种贻贝耐热能力差异的内在机制，42076119，58万元，2021.01-2024.12，负责人
3.科技部港澳台科技合作项目：东海区乌贼生殖调控与规模化繁育关键技术联合研究，100万元，2014.04-2017.03，负责人
4.国家自然科学基金青年项目：基于分子标记的曼氏无针乌贼资源增殖放流效果评估方法研究，22万元，2012.01-2015.12，负责人
5.浙江省自然科学基金重点项目：MiR-122靶向调控大黄鱼“白鳃病毒”发生的分子机制。Z23D060004, 30万元，2023.01-2025.12，负责人
6.浙江省“三农九方”科技协作计划“揭榜挂帅”项目：厚壳贻贝优质苗种繁育、绿色生态养殖及高效利用加工技术研究与示范。2023SNJF065，50万元，2023.01-2024.12，负责人
7.农业部渔业渔政局物种资源保护项目：曼氏无针乌贼增殖放流效果评估和跟踪监测，20万元，2018.01-2018.12，负责人
8.浙江省自然科学基金面上项目：基于线粒体全基因组的乌贼科头足类分类学与系统发育学研究，8万元，2014.01-2016.12，负责人
9.舟山市科技局海洋科技专项项目：曼氏无针乌贼种质资源创新利用研究与示范，15万元，2014.01-2016.12，负责人
10.浙江省科技厅一般项目：大黄鱼免疫相关miRNA的鉴定及功能分析，7万元，2011.07-2014.07，负责人
11.国家自然科学基金面上项目：基于种群基因组学的两种浅海底栖生活蛸科动物的谱系地理格局与适应性分化研究，73万元，2016.01-2019.12，参与人
12.浙江省科技厅重大研发计划：典型岛礁海域生态容量评估及生态修复关键技术研究与应用，250万元，2019.01-2021.12，参与人
代表性论文著作：
Yuxia Wang, Shuangrui Lin, Lezhong Xu, Yingying Ye, Pengzhi Qi, Weifeng Wang, Isabella Buttino, Hongfei Li*,Baoying Guo*. Comparative transcriptomic analysis revealed changes in multiple signaling pathways involved in protein degradation in the digestive gland ofMytilus coruscusduring high-temperatures. Comp Biochem Physiol Part D Genomics Proteomics. 2023, Accepted.
Liao Z, Yang Z, Wang Y, He J, He Z, Zhang X, Buttino I, Qi P, Fan M,Guo B, Yan X, He M*. Molecular characterization of peptidoglycan recognition proteins fromMytilus coruscus. Fish Shellfish Immunol. 2022 Dec;131:612-623. doi: 10.1016/j.fsi.2022.10.018.
Duan X, Dong X, Li J, Lü J,Guo B, Xu K, Ye Y*. The Complete Mitochondrial Genome ofPilumnopeus Makianus(Brachyura: Pilumnidae), Novel Gene Rearrangements, and Phylogenetic Relationships of Brachyura. Genes (Basel). 2022 Oct 25;13(11):1943. doi: 10.3390/genes13111943.
Li, HF; Lin, SR; Qi, PZ; Wang, JT; Fan, MH; Huang, HW; Dong, ZY; Xu, KD;Guo, BY*. Proteomic analysis of the spineless cuttlefishSepiella japonica: Exploratory analyses on the phenomenon of death after spawning. FRONTIERS IN MARINE SCIENCE. 2022 Sept 5; 9: 2296-7745. Doi: 10.3389/fmars.2022.995691.
Feng J, Miao J, Ye Y*, Li J, Xu K,Guo B, Yan X*. Insights into the Deep Phylogeny and Novel Divergence Time Estimation of Patellogastropoda from Complete Mitogenomes. Genes (Basel). 2022 Jul 18;13(7):1273. doi: 10.3390/genes13071273.
Miao J, Feng J, Liu X, Yan C, Ye Y*, Li J*, Xu K,Guo B, Lü Z. Sequence comparison of the mitochondrial genomes of five brackish water species of the family Neritidae: Phylogenetic implications and divergence time estimation. Ecol Evol. 2022 Jun 6;12(6):e8984. doi: 10.1002/ece3.8984.
Qi P, Wu Y, Gu Z, Li H, Li J,Guo B, Liao Z, Yan X*. A novel molluscan TLR molecule engaged in inflammatory response through MyD88 adapter recruitment. Dev Comp Immunol. 2022 Jun;131:104373. doi: 10.1016/j.dci.2022.104373.
Lü J, Xia L, Liu X, Ma Y, Li J*, Ye Y*,Guo B. The mitochondrial genome ofGrapsus albolineatus(Decapoda: Brachyura: Grapsidae) and phylogenetic associations in Brachyura. Sci Rep. 2022 Feb 8;12(1):2104. doi: 10.1038/s41598-022-06080-3.
Zhang X., Li S., He J., Wu Y., Gu Z., Fan M.,Guo B., Buttino I., Liao Z., Yan X. Microalgal feeding preference ofMytilus coruscusand its effects on fatty acid composition and microbes of the digestive gland. Aquac. Rep. 2022, 23:101024(1-10).
Jinyue Yang, Jianyu He, Lu Liu, Menglan He, Xiaolin Zhang, Isabella Buttino,Baoying Guo, Xiaojun Yan, Zhi Liao. Expression profiles of antimicrobial peptides inMytilus coruscus, Aquaculture, 2021, 548, 737709.
Chen Pan, Zhi Liao, Jianyu He, Zhongqi Gu, Chunyue Wang, Meihua Fan, Isabella Buttino,Baoying Guo, Xiaojun Yan, Xiaolin Zhang. Carnosine concentration and expression profiles of carnosine related genes inMytilusafter beta-alanine injection. Journal of Oceanology and Limnology, 2021, doi:10.1007/s00343-021-1078-x.
Huai Yang, Zhongtian Xu,Baoying Guo*, Xiaolin Zhang, Zhi Liao, Pengzhi Qi, Xiaojun Yan. Integrated analysis of miRNAome and transcriptome reveals miRNA-mRNA network regulation inVibrio alginolyticusinfected thick shell musselMytilus coruscus. Molecular Immunology, 2021, 132, 217–226.
Jianhong Feng, Yahong Guo, Chengrui Yan, Yingying Ye, Xiaojun Yan, Jiji Li, Kaida Xu,Baoying Guo, Zhenming Lü. Novel gene rearrangement in the mitochondrial genome ofSiliqua minima(Bivalvia, Adapedonta) and phylogenetic implications for Imparidentia. PLoS ONE, 2021, 16, e0249446
Yahong Guo, Zeqin Fu, Jiantong Feng, Chengrui Yan, Yingying Ye, KaidaXu,Baoying Guo. Wild resource diversity ofMytilus unguiculatusreduced by aquaculture in the Southeast China Sea, Pakistan Journal of Zoologythis, 2021, 53(5), 1669–1676.
Tetsuo Kon, Liyi Pei, Ryota Ichikawa, Chunyan Chen, Ping Wang, Ikuyo Takemura, Yingying Ye, Xiaojun Yan,Baoying Guo, Weiye Li, Hagai Nsobi Lauden, Hiromasa Tabata, Hao Pan, Yoshihiro Omori, Atsushi Ogura, Lihua Jiang. Whole-genome resequencing of large yellow croaker (Larimichthys crocea) reveals the population structure and signatures of environmental adaptation, Scientific Reports, 2021, 11(1), 11235.
Jiantong Feng, Liping Xia, Chengrui Yan, Jing Miao, Yingying Ye*, Jiji Li,Baoying Guo*, Zhen-ming Lü. Characterization of four mitochondrial genomes of family Neritidae (Gastropoda: Neritimorpha) and insight into its phylogenetic relationships.Scientific Reports, 2021, 11(1)：11748
Baoying Guo, Dan Feng, Zhongtian Xu, Pengzhi Qi，Xiaojun Yan. Acute benzo[a]pyrene exposure induced oxidative stress, neurotoxicity and epigenetic change in blood clamTegillarca granosa. Scientific Reports, 2021, 11:18744
Yahong Guo, Hongxia Liu, Jiantong Feng, Jiji Li, Yingying Ye*,Baoying Guo*, Chengkai Qu. Characterization of the complete mitochondrial genomes of two species ofPenaeidae(Decapoda: Dendrobranchiata) and the phylogenetic implications for Penaeoidea.Genomics, 2021,113: 1054-1063
Baoying Guo, Zhongtian Xu, Xiaojun Yan, Isabella Buttino, Jiji Li, Chao Zhou, Pengzhi Qi*. Novel ABCB1 and ABCC transporters are involved in the detoxification of Benzo(α)pyrene in thick shell mussel,Mytilus coruscus.Frontiers in Marine Science, 2020, 7:119
Zhongtian Xu, Yingying Ye, Huai Yang, Ming Xu,Baoying Guo*. The complete mitochondrial genome ofMinous monodactylus(Minoinae: Synanceiidae: Scorpaeniformes) and phylogenetic studies of Scorpaeniformes. Mitochondrial DNA Part B, 2019, 4(1): 1670-1671
Huai Yang, Yingying Ye, Shuobo Liu, Ming Xu,Baoying Guo*. Characterization of complete mitochondrial genome of Nassarius hepaticus (Stenoglossa, Nassariidae). Mitochondrial DNA Part B, 2019, 4(1): 446-447
Shuobo Liu, Chuan Zhang, Pengzhi Qi, Yingying Ye, Hongyue Lv，Baoying Guo*. The M-type mitochondrial genome of hard-shelled mussel:Mytilus coruscus(Mytiloida, mytilidae) with phylogenetic consideration. Mitochondrial DNA Part B, 2019, 4(1):1312-1313
Baoying Guo, Zurong Tang, Changwen Wu, Kaida Xu, Pengzhi Qi*. Transcriptomic analysis reveal an efficient osmoregulatory system in Siberian sturgeonAcipenser baeriinresponse to salinity stress.Scientific Reports, 2018, 8:14353
Baoying Guo, Shuobo Liu, Jiji Li, Zhi Liao, Huihui Liu, Hu Xia, Pengzhi Qi*. Identification and functional characterization of three myeloid differentiation factor 88 (MyD88) isoforms from thick shell musselMytilus coruscus.Fish & Shellfish Immunology, 2018, 83:123-133
Baoying Guo*, Ao Guan, Pengzhi Qi, Zhenming Lv, Changwen Wu, Kaida Xu, Hongling Ping, Huilai Shi. Parentage determination of cuttlefish (Sepiella japonica) based on microsatellite DNA markers.Animal Biology, 2018, 68:1-14
Baoying Guo*, Yu Chen, Chuan Zhang, Zhenming Lv, Kaida Xu, Hongling Ping, Huilai Shi. Characterization of Complete Mitochondrial Genome and Phylogeny ofSepia lycidas(Sepioidea, Sepiidae).Pakistan Journal of Zoology, 2018, 50:1497-1508
Baoying Guo, John P. Wares*. Large-scale gene flow in the barnacleJehlius cirratusand contrasts with other broadly-distributed taxa along the Chilean coast.Peer J, 2017, 5:e2971
Lingmin Xia,Baoying Guo*, Yingying Ye, Jiji Li, Changwen Wu. Determination of genetic diversity of the cuttlefishSepiella japonicainhabiting Chinese coastal waters using the mitochondrial D-loop region: The valuable inspiration to artificial releasing project.Biochemical Systematics and Ecology, 2016, 69:274-282
Baoying Guo*, Yingying Ye, Jiji Li, Pengzhi Qi, Zhenming Lv, Ao Guan, Changwen Wu. Genetic diversity and population structure ofSepiella japonica(Mollusca: Cephalopoda: Decapoda) inferred by 16S rDNA variations.Aquaculture Research, 2016, 47:3016-3022
Baoying Guo*, Changwen Wu, Zhenming Lv, Changlin Liu. Characterisation and expression analysis of two terminal complement components: C7 and C9 from large yellow croaker,Larimichthys crocea.Fish & Shellfish Immunology, 2016, 51: 211-219
Baoying Guo*, Wanchao Wang, Pengzhi Qi, Changwen Wu, Yongjiu Chen, Zhenming Lv. Complete mitochondrial genome of the needle cuttlefishSepia aculeata(Sepioidea, Sepiidae).Mitochondrial DNA Part A, 2016, 27: 67-68
Changwen Wu*, Di Zhang*, Mengyuan Kan*, Zhengming Lv*, Aiyi Zhu*, Yongquan Su*, Daizhan Zhou, Jianshe Zhang, Zhou Zhang, Meiying Xu, Lihua Jiang,Baoying Guo, Ting Wang, Changfeng Chi, Yong Mao, Jiajian Zhou, Xinxiu Yu, Hailing Wang, Xiaoling Weng, Jason Gang Jin, Junyi Ye, Lin He, Yun Liu. The draft genome of the large yellow croaker reveals well-developed innate immunity.Nature Communications, 2014, 5:1-7
Baoying Guo, Pengzhi Qi, Aiyi Zhu, Zhenming Lv, Wanchao Wang, Changwen Wu*. Isolation and characterization of new polymorphic microsatellite markers from the cuttlefishSepiella maindroni(Cephalopoda; Sepiidae).Genetics Molecular Research, 2013, 12: 2736-2379
苗菁，李继姬，叶莹莹*，郭宝英，徐开达。陆川小笠贝(Lottia luchuana)线粒体全基因组测序及笠贝科系统发育分析。水生生物学报，1-14
董震宇，杨槐，郭宝英*，叶莹莹，祁鹏志，迟长凤，徐开达。曼氏无针乌贼(Sepiella japonica)维甲酸X受体(RXR)cDNA的克隆与表达。中国水产科学，2022，29(06):814-824。
严小军，祁鹏志，郭宝英，李继姬。Nrf2参与水生动物氧化应激调控的研究进展。海洋与湖沼，2021,52(04)
许中天，董震宇，李继姬，祁鹏志，郭宝英*。苯并[a]芘（BaP）急性暴露对泥蚶消化腺的毒性效应及其应对机制初探。渔业科学进展，2021-11-11
夏立萍，徐鸣，郭宝英，叶莹莹。等边浅蛤线粒体全基因组测序和系统发育研究。浙江海洋大学学报(自然科学版). 2021,40(02)
董震宇，杨槐，孙扬，叶莹莹，祁鹏志，郭宝英*。甲状腺激素在无脊椎动物中的研究进展。浙江海洋大学学报，2021,40(06)
田起宏，张琳，殷林飞，郭宝英，汪保华，杨俊林。科学基金国际合作项目2019年度评审与资助情况及未来工作思考。中国科学基金. 2020,34(01)
刘硕博，唐祖蓉，申望，叶莹莹，陈晓磊，祁鹏志，郭宝英*。基于F型mtDNA D-Loop的厚壳贻贝(Mytilus coruscus)群体遗传多样性研究。海洋与湖沼，2019,50(2):355-364
孙扬，郭宝英*，祁鹏志，陈宇，唐祖蓉，刘硕博。基于转录组的曼氏无针乌贼SSR与SNP位点信息分析。浙江海洋大学学报(自然科学版). 2019,38(02)
毋玉婷，郭宝英*，祁鹏志，吕振明，吴常文，史会来，平洪领.曼氏无针乌贼Phb2基因的克隆和其在不同生长阶段的表达分析.中国水产科学，2018, 25:9-17
管奥，毋玉婷，陈宇，孙杨，祁鹏志，郭宝英*.曼氏无针乌贼转录组微卫星特征分析.渔业科学进展，2018，39:144-151
专利：
1.郭宝英，周超，张彩明。中国发明专利，金乌贼幼苗养殖饲料，专利号：ZL201210474597.4
2.郭宝英，朱爱意，周雷文。中国发明专利，低氨氮超集约养殖系统，专利号：ZL201410833133.7
3.郭宝英；朱爱意；周雷文。中国发明专利，多用养殖水箱，专利号：ZL 2013 2 0862582.5
4.郭宝英，尚晓明。中国发明专利，无气石养殖增氧装置，专利号：ZL201310725431X
5.郭宝英，朱爱意，周雷文。中国发明专利，无气石养殖容器，专利号：ZL201310725475.2
6.郭宝英，徐佳晶，尚晓明。中国发明专利，工厂化养殖循环水处理装置，专利号：ZL201210539944.7
7.郭宝英，朱爱意，周雷文。中国实用新型专利，多用养殖水箱，专利号：ZL201320862582.5
8.郭宝英，尚晓明。中国实用新型专利，射流式增氧组件，中国实用新型专利：ZL2013200862442.8
9.郭宝英，徐佳晶，李海锋。中国实用新型专利，室外线杀菌养殖罐，专利号：ZL201420864514.7
曾获得的奖项及荣誉荣誉：
1. 2022年度中国发明协会发明创业奖成果奖二等奖：曼氏无针乌贼种苗繁育技术研究与资源增殖效果评价，1/5
2. 2022年度中国产学研合作创新与促进奖优秀奖：长江口外厚壳贻贝环境适应性研究及种苗繁育关键技术，3/10
3. 2022年度中国商业联合会科学技术奖一等奖：长江口外厚壳贻贝环境适应性研究及健康绿色养殖产业化示范，4/15
4. 2021年度中国发明协会发明创业奖二等奖：浙江沿海重要贝类渔业资源综合开发及利用，2/8
5. 2021年度中国产学研合作创新与促进奖个人奖
6. 2019年度中国商业联合会科学技术奖二等奖：活海水产品现代物流关键技术研究集成与示范，6/16
7. 2019年度海洋科学技术奖二等奖：浙江近海曼氏无针乌贼资源规模化修复关键技术研究与应用，4/10
8. 2019年度中国商业联合会科学技术奖二等奖：浙江近海曼氏无针乌贼繁育与资源规模化修复关键技术研究与应用，4/10
9. 2012年西藏自治区科学技术奖二等奖：西藏黑斑原鮡生物学与人工繁育技术研究，5/12
10.舟山市第七届青年科技奖，2017
11.舟山市“三八”红旗手，2017
12.浙江省151人才第三层次，2015
13.舟山市111人才第二层次，2011
