
姓名:迟长凤
职称:教授
导师身份:浙江海洋大学博士生导师、上海海洋大学博士生导师
研究方向:海洋生物资源发掘与开发利用
教授课程:海洋生物学(双语)、鱼类生理学
Email:chicf@zjou.edu.cn
学习工作简历
2015年09月至今浙江海洋大学教授
2015年01月至2016年01月美国密歇根大学访问学者
2010年11月至2015年08月浙江海洋学院副教授
2009年09月至2010年10月浙江海洋学院讲师
2007年09月至2009年07月浙江大学博士后
2004年09月至2007年06月中国海洋大学博士
2001年09月至2004年07月山东农业大学硕士
1997年09月至2001年07月山东农业大学学士
研究兴趣
头足类和鱼类生殖调控、无脊椎动物神经肽生理功能、头足类和鱼类神经内分泌免疫。
科研项目
1.国家自然科学基金(面上),曼氏无针乌贼神经肽-FMRFa样肽(FLPs)调控生殖网络机制探究,项目编号:32473136,2025.1.1-2028.12.31,主持。
2.浙江省自然科学基金项目,曼氏无针乌贼神经肽F及其受体调控摄食机制探究,项目编号:LTGN24C190005,2024.1.1-2026.12.31。主持。
3.省属高校基本业务费,东海名贵鱼类经济性状相关基因功能与调控网络解析,项目编号:2024J005,2024.1.1-2025.12.31,主持。
4.浙江省自然科学基金项目,曼氏无针乌贼神经肽FMRFamide及其受体调节缠卵腺分泌功能初探,项目编号:LY20C190007,2020.1.1-2022.12.31。主持。
5.国家自然科学基金(面上),基于生殖调控轴理论的人工养殖曼氏无针乌贼性早熟机理研究,项目编号:31872547,2019.01-2022.12。主持。
6.舟山市科技计划,FMRF酰胺肽在虎斑乌贼苗种繁育中的作用,项目编号:2016C41016,2016.09-2019.08。主持。
7.浙江省自然科学基金项目,神经肽LFRFamide对虎斑乌贼生殖发育的调控机理研究,项目编号:LY15C190010,2015.01-2017.12。主持。
8.欧盟FP7合作项目,Parasite risk assessment with integrated tools in EU fish production value chains,项目编号:EC ref 312068,2013.02-2016.02。主持(子课题)。
9.国家科技部863计划课题,新养殖海水种类苗种繁育技术,项目编号:2012AA10A413-5,2012.01-2015.12。主持(子课题)。
10.国家自然科学基金(青年),曼氏无针乌贼神经肽对生殖发育的调控机理研究,项目编号:31001109,2010.01-2012.12。主持。
代表性论文著作(近5年)
[1]Zhou Xu, Jun-jie Li, Shuang Li, Hui-hui Liu, and Chang-feng Chi*. 5-HTR1D and 5-HTR2B regulatedCryptocaryonirritans-induced inflammatory response of large yellow croakerLarimichthyscrocea[J].International Journal of Biological Macromolecules, 2025, 145704.
[2]Xu Zhou1· Shu‑fan Yu1· Jia‑yin Qiu1· Jian‑jun Xie1· Shuang Li1· Li‑bing Zheng2,*, Chang‑feng Chi1*. Involvement ofPRQFVamide‑related peptide in immune response ofSepiellajaponicathrough suppressing nitric oxide production [J].Aquaculture International, 2025, 33:92.
[3]Wen-Bo Cui1,†, Prisca JohnIssangya1,†, Shuang Li1, Xu Zhou1, Li-Bing Zheng1,2,*and Chang-Feng Chi1,*. Identification, Localization, and Expression Analysis of 5-HT6 Receptor, and Primary Role inSepiellajaponica, Based on Sex andLife Stage [J].Diversity, 2025, 17(2), 104.
[4]Jian-junXie1, Ying Li1, Jun-hong Wu, Pei-xuan Fang, Shuang Li, Xu Zhou, Chang-feng Chi*. FMRFamideG protein-coupled receptors (GPCR) in the cuttlefishSepiellajaponica: Identification, characterization and expression profile [J].Neuropeptides, 2025, 109,102491.
[5]LI Shuang1, HAO Qing1, QIU Jiayin1, ZHOU Xu1, CHI Changfeng1*, and ZHENG Libing2*. The first non-chordates QRFP-Like peptide receptor gene in the cephalopodSepiellajaponica: identification, characterization and possible role in food intake [J].Journal of Ocean University of China, 2025, 24 (1): 195-208.
[6]Xu Zhou, Jun-Jie Li, Shuang Li, Hui-Hui Liu, Dong-Dong Xu, Chang-Feng Chi*, Li-Bing Zheng*. Transcriptomic analysis of large yellow croaker (Larimichthyscrocea) reveals the suppression of the inflammatory response fromCryptocaryonirritansinfection [J].Fish and Shellfish Immunology, 2024, 144, 109258.
[7]QIU Jiayin#, SUN Lianlian#, LI Shuang, ZHOU Xu, CHI Changfeng*, and ZHENG Libing. Identification and expression profile of a neuropeptideLFRFamide-like gene during different stages of gonadal development in the cephalopodSepiapharaonis[J].Journal of Ocean University of China, 2024, 23 (2): 499-508.
[8]Gong Li,Jiayin Qiu,Huimin Cao,Libing Zheng*,Changfeng Chi*, Shuang Li, Xu Zhou. Molecular characterization, expression and in situ hybridization analysis of a pedal peptide/orcokinin-type neuropeptide in cuttlefishSepiellajaponica[J].Current Protein & Peptide Science, 2024, 25, 326-338.
[9]Hui-Min Cao1, Jun-Hong Wu1, Shuang Li, Xu Zhou, Li-Bing Zheng, Chang-Feng Chi*. A Na channel receptor ofFMRFamidein the cephalopodSepiellajaponica: Identification,characterisation, and expression profiling during different stages of gonadal development [J].Neuropeptides, 2024, 106, 102437.
[10]Xu Zhou, Pei-Xuan Fang, Hui-Min Cao, Jian-JunXie, Shuang Li, Chang-Feng Chi*. Molecular characterization and expression of twenty interleukin-17 transcripts in the common Chinese cuttlefish (Sepiellajaponica) in response toVibrioharveyiinfection [J].Fish and Shellfish Immunology, 2023, 140, 108903.
[11]Wei Cao,Yinghui Dong,Yusong Geng,Siqi Bi,Zhihong Liu,Liqing Zhou,Xiujun Sun,Sudong Xia,Changfeng Chi*, and Biao Wu*. Comprehensive analysis ofWwhole-transcriptome profiles in response to acute hypersalineCchallengeinchineserazor clamSinonovaculaconstrictab[J].Biology, 2023, 12, 106.
[12]Jia-yin Qiu, Li-bing Zheng* and Chang-feng Chi*. Identification, characterization, and expression of aPRQFVamide-related peptide in cephalopodSepiellajaponica[J].Frontiers in Marine Science, 2022, 9, 805209.
[13]Libing Zheng,Huimin Cao,Jiayin Qiu and Changfeng Chi*. Involvement in inhibitory effect ofFMRFamideon NO production during immune defense inSepiellajaponica[J].Frontiers in Immunology, 2022, 13: 1-10.
[14]Libing Zheng,Jiayin Qiu,Huihui Liu,Changfeng Chi*, Longshan Lin*. Potential anticancer activity analysis ofpiscidin5-like fromLarimichthyscrocea[J].ActaOceanologicaSinica, 2022, 41(3): 53-60.
[15]Ran Xiao,Zuting Guo, Li‑bing Zheng, Wei Huang, Chang‑feng Chi*, Bao Lou*. Neuropeptide FF‑related gene in fish (Larimichthyspolyactis): identification, characterization, and potential anti‑inflammatory function [J].Molecular Biology Reports, 2022.
[16]Chang-Pu Song, Lian-lian Sun, Li-bing Zheng, Chang-feng Chi*. Gonadotropin-releasing hormone-like gene in the cephalopod,Sepiapharaonis: characterization, expression analysis, and localization in the brain [J]. Invertebrate Reproduction & Development, 2021, 65(3): 226-234.
[17]Libing Zheng,Jiayin Qiu,Huihui Liu,Huilai Shi*,Changfeng Chi*, Ying Pan. Molecular characterization and antiparasitic activity analysis of a novelpiscidin5-like type 4 fromLarimichthyscrocea[J].Molecular Immunology, 2021, 129, 12-20.
[18]Yang Zhu, Lian-lian Sun, Jun-hong Wu, Hui-hui Liu, Li-bing Zheng, Zhen-ming Lü and Chang-feng Chi*. AnFMRFamideneuropeptide in cuttlefishSepiapharaonis: identification, characterization, and potential function [J].Molecules, 2020, 25, 1636.
[19]Ying Li,Zihao Cao, Haifeng Li,Huihui Liu,Zhenming Lü,Changfeng Chi*. Identification, Characterization, and Expression Analysis of aFMRFamide-Like Peptide Gene in the Common Chinese Cuttlefish (Sepiellajaponica) [J].Molecules,2018, 23 (4), 742.
[20]Zi-hao Cao, Lian-lian Sun, Chang-feng Chi*, Hui-hui Liu, Li-qing Zhou, Zhen-ming Lv, Chang-wen Wu. Molecular cloning, expression and cellular localization of anFMRFamide-like peptide gene (LFRFamide) in the cuttlefishSepiellajaponica[J].Peptides, 2016, 80: 40-47.