姓名:杨静文
职称:教授
导师身份:浙江海洋大学博士生导师
研究方向:海洋生物学分子及细胞生物学方向
Email：yangjingwen@zjou.edu.cn
学习工作简历
2003年9月至2007年7月山东理工大学学士
2007年9月至2010年7月中国科学院海洋研究所硕士
2010年9月至2013年6月浙江大学动物科学学院博士
2013年7月至2018年8月浙江海洋大学海洋科学与技术学院讲师
2017年9月至2018年9月加州大学旧金山分校CSC访问学者
2018年9月至2022年12月浙江海洋大学海洋科学与技术学院副教授
2023年1月至今浙江海洋大学海洋科学与技术学院教授
研究兴趣
GPCR参与的海洋生物生理功能调控
海洋生物神经内分泌调控网络
科研项目
1、大黄鱼现代牧养技术创新及行为生态机制研究(2024J002)，浙江省高校基本科研业务费，2024.01-2025.12（主持）
2、大黄鱼褪黑素信号系统特征及其生殖调控机理研究(42076130)，国家自然科学基金面上项目，2021.01-2024.12（主持）
3、大黄鱼神经肽Y2亚族受体的信号转导机制及其生理功能研究(41606150)，国家自然科学基金青年项目，2017.01-2019.12（主持）
4、刺参CRH/CRHR系统特征及其夏眠调控研究(2019C21020)，舟山市科学技术项目，2019.01-2021.12（主持）
5、曼氏无针乌贼生殖生长调控神经肽高活性表达研究及评价(2017C32074)，浙江省公益技术研究项目，2016.07-2018.06（主持）
代表性论文著作
1.Liang,Xudong,Jixiu Wang,Baoyi Huang,Haojie Yuan,Yucheng Ren,Chenqian Wu,Tianming Wang*, andJingwen Yang*, Functional Involvement of Melatonin and Its Receptors in Reproductive Regulation of the Marine Teleost, Large Yellow Croaker (Larimichthyscrocea), Fishes, 2025,10, 1: 28.
2.Guangbo Zhang,Zhiqing Ye,Zhijing Jiang,Chenqian Wu,Lifei Ge,Jixiu Wang,Xiuwen Xu,Tianming Wang*,Jingwen Yang*.Circadian Patterns and Photoperiodic Modulation of ClockGeneExpression and Neuroendocrine Hormone Secretion in the Marine TeleostLarimichthyscrocea.Chronobiology International 2024, 41(3): 329–46.
3.Jixiu Wang,Chenqian Wu,Zhiqing Ye,Xiaolong Yin,Weiye Li,Guangbo Zhang,Zhijing Jiang,Xudong Liang, Ying Wei,Lifei Ge,Xiuwen Xu,Tianming Wang*,Jingwen Yang*, Cortisol suppresses lipopolysaccharide-induced in vitro inflammatory response of large yellow croaker (Larimichthyscrocea) via theglucocorticoid receptor and p38 mitogen-activated protein kinase pathways, Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology,2025, 275, 111046.
4.Jiaqian Feng#,Jingwen Yang#,Zhijing Jiang#,Naiming Zhou,Xue Liu,Guangbo Zhang,Xiaojun Yan,Jixiu Wang,Xiuwen Xu, Su Guo,Tianming Wang. Melatonin modulates the hypothalamic-pituitary neuroendocrine axis to regulate physiological color change in teleost fish. International Journal of Biological Sciences, 2023, 19(9): 2914-2933.
5.Xue Liu,Jiaqian Feng,Zhijing Jiang,Guangbo Zhang,Xiuwen Xu,Jixiu Wang,Jingwen Yang* and Tianming Wang*.Functional characterization of twocorticotropin-releasing hormone receptors inLarimichthyscrocea.Frontiers in Marine Science.2023, 10: 1-14.
6.Tianming Wang, Jing Liang,Xiaowei Xiang, Xu Chen, Bing Zhang,Naiming Zhou, Wei Huang,Jingwen Yang*. Pharmacological characterization, cellular localization and expression profile of NPY receptor subtypes Y2 and Y7 in large yellow croaker,Larimichthyscrocea.Comparative biochemistry and physiology.Part B, Biochemistry & molecular biology, 2019, 238:110347.
7.Jiaqian Feng, Tao Han,Yuexing Zhang, Bing Zhang,Dexiang Huang,Tianming Wang,Jingwen Yang*.Molecular characterization and biological function of CXCR1 inNocardiaseriolae-infected largemouth bass (Micropterussalmoides).Tissue Cell, 2021, 72:101551.
8.Tianming Wang#, Zheng Cao#,Zhangfei Shen#,Jingwen Yang, Xu Chen, Zhen Yang,KeXu,XiaoweiXiang,QiuhanYu,YiminSong,WeiweiWang,YananTian, Lina Sun,LibinZhang, SuGuo,NaimingZhou.Existence and functions of akisspeptinneuropeptide signaling system in a non-chordate deuterostome species.Elife, 2020, 9: e53370.
9.Tianming Wang, Xu Chen,Ke Xu, Bing Zhang,Dexiang Huang,Jingwen Yang*.Apoptosis Induction and Detection in a Primary Culture of Sea Cucumber Intestinal Cells.Journal of Visualized Experiments, 2020, 155.
10.Tianming Wang*, Jing Liang,Xiaowei Xiang,Jiajie Yuan, Xu Chen,Xingwei Xiang,Jingwen Yang*.Functional identification and expressional responses of large yellow croaker (Larimichthyscrocea) interleukin-8 and its receptor.Fish & Shellfish Immunology, 2019, 87: 470-477.
11.Jingwen Yang,Yuchao Xu,Ke Xu,Hongling Ping,Huilai Shi,Zhenming Lv,ChangwenWu,TianmingWang*. Molecular cloning and transcriptional analysis of anpyreceptor-like in commonchinesecuttlefishSepiellajaponica. Chinese Journal of Oceanology and Limnology, 2018, 36(3): 892-904.
12.Jingwen Yang，Yunjun Yan，Xiaowei Xiang，Yuchao Xu，Naiming Zhou*，Tianming Wang*，Detection of ligand-activated G protein coupled receptor internalization by confocal microscopy. Journal of Visualized Experiments, 2017, (122):55514.
13.Jingwen Yang,Zhangfei Shen,Xue Jiang,Huipeng Yang,Haishan Huang, Lili Jin,Yajie Chen,Liangen Shi*,Naiming Zhou*.Agonist-activatedBombyxcorazoninreceptor is internalized via anarrestin-dependent andclathrin-independent pathway. Biochemistry, 2016, 55(28): 3874-3887.
14.Jingwen Yang,Huihui Liu, Gang Zheng,Xiaowei Xiang,Zhenming Lv*,Tianming Wang*.CathepsinL of the sea cucumberApostichopusjaponicusmolecular characterization and transcriptional response to Vibriosplendidusinfection.Fish & Shellfish Immunology, 2016, 49: 387-395.
15.Yunjun Yan,Tianming Wang, Wan Liu,Changwen Wu,Aiyi Zhu,Changfeng Chi,Zhenming Lv*,Jingwen Yang*.Identification and Expression Profile of the Gonadotropin-Releasing Hormone Receptor in Common Chinese Cuttlefish,Sepiellajaponica.Journal of Experimental Zoology Part A-Ecological Genetics and Physiology, 2016, 325(7): 453-466.
16.Zhenming Lv, Wan Liu,Liqing Liu,Tianming Wang,Huilai Shi,Hongling Ping,Changfeng Chi,Jingwen Yang*,Changwen Wu.Cloning, Characterization, and Expression Profile of Estrogen Receptor in Common Chinese Cuttlefish,Sepiellajaponica.Journal of Experimental Zoology Part A-Ecological Genetics and Physiology, 2016, 325(3): 181-193.
17.Jingwen Yang,Haishan Huang,Huipeng Yang,Xiaobai He,Xue Jiang, Ying Shi,DamirinAlatangaole,Liangen Shi*,Naiming Zhou*. Specific activation of the G protein-coupled receptor BNGR-A21 by the neuropeptidecorazoninfrom the silkworm,Bombyxmori, dually couples to theG(q) and G(s) signaling cascades. Journal of Biological Chemistry, 2013, 288(17): 11662-11675.
18.Jingwen Yang,Suping Zhang*.The radular morphology of Nassariidae(Gastropoda:Caenogastropoda) from China, Chinese Journal of Oceanology and Limnology, 2011, 29(5): 1023-1032.
19.Jingwen Yang,Suping Zhang*.A new spceies of Nassarius(Gastropoda,Nassariidae) from the northern China seas,ActaOceanologicaSinica, 2011, 30(6): 82-85.
